Inter 0 Eintracht Frankfurt 1 (0-1 on agg)
Round of 16 2nd leg – Eintracht Frankfurt win 1-0 on aggregate
March 14, 2019
0
Arsenal 3 Rennes 0 (4-3 on agg)
Round of 16 2nd leg – Arsenal win 4-3 on aggregate
March 14, 2019
Benfica 3 Dinamo Zagreb 0 (AET 3-1 on agg)
Round of 16 2nd leg – Benfica win 3-1 on aggregate AET
March 14, 2019
Villarreal 2 Zenit Saint Petersburg 1 (5-2 on agg)
Round of 16 2nd leg – Villarreal win 5-2 on aggregate
March 14, 2019
Slavia Prague 4 Sevilla 3 (AET 6-5 on agg)
Round of 16 2nd leg – Slavia Prague win 6-5 on aggregate AET
March 14, 2019
Salzburg 3 SSC Napoli 1 (3-4 on agg)
Round of 16 2nd leg – Napoli win 4-3 on aggregate
March 14, 2019
FC Krasnodar 1 Valencia 1 (2-3 on agg)
Round of 16 2nd leg – Valencia win 3-2 on aggregate
March 14, 2019
Dynamo Kiev 0 Chelsea 5 (0-8 on agg)
Round of 16 2nd leg – Chelsea win 8-0 on aggregate
March 14, 2019
Barcelona 5 Lyon 1 (5-1 on agg)
Round of 16 2nd leg – Barcelona win 5-1 on aggregate
March 13, 2019
Bayern Munich 1 Liverpool 3 (1-3 on agg)
Round of 16 2nd leg – Liverpool win 3-1 on aggregate
March 13, 2019